Methyl rosmarinate

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

迷迭香酸甲酯是一种非竞争性酪氨酸酶抑制剂，从 Rabdosia serra 中分离出来，对蘑菇酪氨酸酶的 IC50 为 0.28 mM。迷迭香酸甲酯具有抗氧化和抗真菌活性。它对酪氨酸酶、α±-葡萄糖苷酶和基质金属蛋白酶-1 (MMP-1) 具有抑制活性。

Methyl rosmarinate is a noncompetitive tyrosinase inhibitor which is isolated from Rabdosia serra, with an IC50 of 0.28 mM for mushroom tyrosinase.Methyl rosmarinate shows antioxidative, and antifungal activities.?It has inhibitory activities against tyrosinase, α±-glucosidase, and matrix metalloproteinase-1 (MMP-1).An initial microtiter dilution assay indicated activity of compounds against S. carnosus LTH1502, whereas esters with chain lengths, RA, n-Methyl rosmarinate (RE1), n-dodecyl rosmarinate (RE12), and n-octadecyl rosmarinate (RE18) were used in a time-kill assay S. carnosus LTH1502. Compounds were added at 0.75 mM in the log phase, 5 mM in the exponential phase, 10 mM in the stationary phase. RA had no effect in the lag and exponential phase but decreased cell counts during the stationary phase. In contrast, RE1 and RE12 decreased cell number in all three phase, will RE12 reducing counts most rapidly. Addition of RE18 did not affect regardless of the growth phase.

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Proteasome/Ubiquitin

Tyrosinase

Tyrosinase|Antifection|MMP

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99353-00-1

374.4

C19H18O8

>98% (HPLC)

In Vitro:?DMSO : 100 mg/mL (267.14 mM)

OC1=C(O)C=CC(/C=C/C(O[C@@H](C(OC)=O)CC2=CC(O)=C(O)C=C2)=O)=C1

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(-20℃)

With Ice Pack

≥ 2 years